RAB7A 抗体
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- 抗原 See all RAB7A 抗体
- RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This RAB7A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Human RAB7 aa 50-150
- 克隆位点
- 8H10
- 亚型
- IgG
- Top Product
- Discover our top product RAB7A Primary Antibody
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anti-RAB7A, Member RAS Oncogene Family (RAB7A) (C-Term) antibody
RAB7A 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, 猴, Avian, Cat, 驴, 山羊, 豚鼠, Hamster, 马, Pig, 兔, 绵羊 WB, IF 宿主: 山羊 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 176-204), (C-Term) antibodyRAB7A 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21394 unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 101-207) antibodyRAB7A 适用: 人, 小鼠 WB, ELISA, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 176-204) antibodyRAB7A 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 110-177) antibodyRAB7A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) antibodyRAB7A 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (AA 1-207) antibodyRAB7A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (C-Term) antibodyRAB7A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAB7A, Member RAS Oncogene Family (RAB7A) (C-Term) antibodyRAB7A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
- 别名
- RAB7 (RAB7A 产品)
- 背景
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Synonyms: Ras-related protein Rab-7a, RAB7A
Background: Key regulator in endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth-factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism. Also involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes, pathogen-induced phagosomes (or vacuoles) and autophagosomes. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes. Plays important roles in microbial pathogen infection and survival, as well as in participating in the life cycle of viruses. Microbial pathogens possess survival strategies governed by RAB7A, sometimes by employing RAB7A function (e.g. Salmonella) and sometimes by excluding RAB7A function (e.g. Mycobacterium). In concert with RAC1, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts. Controls the endosomal trafficking and neurite outgrowth signaling of NTRK1/TRKA. Regulates the endocytic trafficking of the EGF-EGFR complex by regulating its lysosomal degradation.
- 基因ID
- 7879
- UniProt
- P51149
- 途径
- EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
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