PTPN12 抗体 (AA 1-100)
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- 抗原 See all PTPN12 抗体
- PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))
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抗原表位
- AA 1-100
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTPN12 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PTPN12
- 亚型
- IgG
- Top Product
- Discover our top product PTPN12 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))
- 别名
- PTPN12 (PTPN12 产品)
- 别名
- PTP-PEST antibody, PTPG1 antibody, P19-PTP antibody, PTP-P19 antibody, Ptpg1 antibody, RKPTP antibody, protein tyrosine phosphatase, non-receptor type 12 antibody, PTPN12 antibody, Ptpn12 antibody
- 背景
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Synonyms: Protein tyrosine phosphatase G1, Protein tyrosine phosphatase non receptor type 12, Protein-tyrosine phosphatase G1, PTN12_HUMAN, PTP PEST, PTP-PEST, PTPG1, Ptpn12, Tyrosine protein phosphatase non receptor type 12, Tyrosine-protein phosphatase non-receptor type 12.
Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
- 基因ID
- 5782
- UniProt
- Q05209
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