PRPF8 抗体
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- 抗原 See all PRPF8 抗体
- PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This PRPF8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within 1200 of human PRPF8.
- 克隆位点
- 1A7
- 亚型
- IgG
- Top Product
- Discover our top product PRPF8 Primary Antibody
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anti-PRP8 Pre-mRNA Processing Factor 8 (PRPF8) antibody
PRPF8 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PRP8 Pre-mRNA Processing Factor 8 (PRPF8) (AA 1-100) antibodyPRPF8 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-PRP8 Pre-mRNA Processing Factor 8 (PRPF8) antibodyPRPF8 适用: 人 WB, FACS, ICC, DB 宿主: 小鼠 Monoclonal 2834C1a unconjugated
anti-PRP8 Pre-mRNA Processing Factor 8 (PRPF8) (C-Term) antibodyPRPF8 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PRP8 Pre-mRNA Processing Factor 8 (PRPF8) (AA 2239-2273), (C-Term) antibodyPRPF8 适用: 人 WB 宿主: 兔 Polyclonal RB49150 unconjugated
anti-PRP8 Pre-mRNA Processing Factor 8 (PRPF8) (AA 2037-2170) antibodyPRPF8 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-PRP8 Pre-mRNA Processing Factor 8 (PRPF8) antibodyPRPF8 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PRP8 Pre-mRNA Processing Factor 8 (PRPF8) (AA 360-409) antibodyPRPF8 适用: 人, 小鼠, 大鼠, 非洲爪蟾, 斑马鱼, 犬, 小鸡, Cow, 豚鼠, 马, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-PRP8 Pre-mRNA Processing Factor 8 (PRPF8) (N-Term) antibodyPRPF8 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))
- 别名
- PRPF8 (PRPF8 产品)
- 别名
- id:ibd1257 antibody, ik:tdsubc_2a9 antibody, im:7141966 antibody, tdsubc_2a9 antibody, wu:fb37c02 antibody, wu:fb73e06 antibody, xx:tdsubc_2a9 antibody, zgc:56504 antibody, hprp8 antibody, prp-8 antibody, prp8 antibody, prpc8 antibody, rp13 antibody, HPRP8 antibody, PRP8 antibody, PRPC8 antibody, RP13 antibody, SNRNP220 antibody, AU019467 antibody, D11Bwg0410e antibody, DBF3/PRP8 antibody, Prp8 antibody, Sfprp8l antibody, pre-mRNA processing factor 8 antibody, pre-mRNA processing factor 8 S homeolog antibody, Prpf8 antibody, prpf8 antibody, prpf8.S antibody, PRPF8 antibody
- 背景
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Synonyms: Pre-mRNA-processing-splicing factor 8, 220 kDa U5 snRNP-specific protein, PRP8 homolog, Splicing factor Prp8, p220, PRPF8, PRPC8
Background: PRP8, also designated pre-mRNA-processing-splicing factor 8, is a highly conserved nuclear protein and a central component of the catalytic core of the spliceosome, where it may be involved in various molecular rearrangements. PRP8, which is widely expressed, plays a role in transesterification reactions that regulate splicesome-induced pre-mRNA splicing. Specifically, PRP8 interacts with the GU dinucleotide at the 5' splice site (5'SS) and forms a specific UV-inducible cross-link. It also interacts functionally with the 3'SS, affecting the efficiency of the second catalytic step. PRP8 may play a role in the first transesterification step, as PRP8 mutations that prohibit negative regulation of PRP28 or PRP44/Brr2 subsequently block U4 activation. In addition, PRP8 interacts with a conserved region of U6 that is instrumental in the formation of the catalytic core of the spliceosome.
- 基因ID
- 10594
- UniProt
- Q6P2Q9
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