PPP1CB 抗体
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- 抗原 See all PPP1CB 抗体
- PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This PPP1CB antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein corresponding to human PPP1CB aa 100-327.
- 克隆位点
- 6G6
- 亚型
- IgG
- Top Product
- Discover our top product PPP1CB Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IP(1-2 μg) - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))
- 别名
- PPP1CB (PPP1CB 产品)
- 别名
- PP-1B antibody, PP1B antibody, PP1beta antibody, PPP1CD antibody, 1200010B19 antibody, ik:tdsubc_2f2 antibody, si:zc214p16.4 antibody, wu:fa09h01 antibody, wu:fa11e06 antibody, xx:tdsubc_2f2 antibody, PP2CB antibody, Ppp1cb antibody, protein phosphatase 1 catalytic subunit beta antibody, protein phosphatase 1, catalytic subunit, beta isoform antibody, protein phosphatase 1, catalytic subunit, beta isozyme L homeolog antibody, protein phosphatase 1, catalytic subunit, beta isozyme antibody, serine/threonine-protein phosphatase PP1-beta catalytic subunit antibody, protein phosphatase 1B, magnesium dependent, beta isoform antibody, PPP1CB antibody, Ppp1cb antibody, ppp1cb.L antibody, ppp1cb antibody, LOC100224238 antibody, Ppm1b antibody
- 背景
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Synonyms: Serine/threonine-protein phosphatase PP1-beta catalytic subunit, Protein phosphatase 1 catalytic subunit beta, PP-1B, PPP1CD, PP1beta
Background: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective.
- 基因ID
- 5500
- UniProt
- P62140
- 途径
- M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism
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