PKC iota 抗体 (AA 181-280) (Biotin)
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- 抗原 See all PKC iota (PRKCI) 抗体
- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
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抗原表位
- AA 181-280
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PKC iota antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PKC iota/PKCI
- 亚型
- IgG
- Top Product
- Discover our top product PRKCI Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
- 别名
- PKC iota (PRKCI 产品)
- 别名
- DXS1179E antibody, PKCI antibody, nPKC-iota antibody, aPKC[l] antibody, hal antibody, has antibody, PRKCI antibody, PKC antibody, 2310021H13Rik antibody, AI427505 antibody, PKClambda antibody, Pkci antibody, Pkcl antibody, Prkcl antibody, aPKClambda antibody, mKIAA4165 antibody, protein kinase C iota antibody, protein kinase C, iota antibody, PRKCI antibody, prkci antibody, Prkci antibody
- 背景
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Synonyms: aPKC lambda/iota, aPKC-lambda/iota, Atypical protein kinase C lambda/iota, Atypical protein kinase C-lambda/iota, DXS1179E, KPCI_HUMAN, MGC26534, nPKC iota, nPKC-iota, nPKCiota, PKC lambda, PKCI, PKCiota, PKClambda, PRKC iota, PRKC lambda/iota, PRKC-lambda/iota, PRKCI, Protein kinase C iota, Protein kinase C iota type.
Background: This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008]
- 基因ID
- 5584
- UniProt
- P41743
- 途径
- Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation
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