PGC1 alpha + beta (AA 601-700) 抗体 (AbBy Fluor® 750)
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- 抗原
- PGC1 alpha + beta
- 抗原表位
- AA 601-700
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- AbBy Fluor® 750
- 应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 特异性
- 76 % homology with PGC1 beta
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PPARGC1A
- 亚型
- IgG
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- 应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PGC1 alpha + beta
- 别名
- PGC1 alpha , beta
- 背景
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Synonyms: LEM6, PGC-1 Alpha, PGC1 Alpha, Ligand effect modulator 6, Peroxisome prolerative activated receptor, gamma, coactivator 1 alpha, Peroxisome prolerative activated receptor, gamma, coactivator 1 , Peroxisome prolerator activated receptor gamma coactivator 1 alpha, PGC 1 alpha, PGC 1 alpha, PGC 1v, PGC1, PGC1alpha, PGC1A, PGC1v, PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6, PPAR gamma coactivator 1 alpha, PPAR gamma coactivator 1, PPAR gamma coactivator variant form, PPARGC 1 alpha, PPARGC1A.
Background: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity (referenced from entrez gene.
- 基因ID
- 10891
- UniProt
- Q9UBK2
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