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PARP2 抗体

PARP2 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Monoclonal 19A1 unconjugated
产品编号 ABIN6944437
发货至: 中国
  • 抗原 See all PARP2 抗体
    PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
    适用
    • 45
    • 37
    • 10
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 58
    • 2
    • 1
    克隆类型
    • 52
    • 9
    单克隆
    标记
    • 29
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PARP2 antibody is un-conjugated
    应用范围
    • 38
    • 25
    • 8
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant protein within the C-terminus of human PARP2.
    克隆位点
    19A1
    亚型
    IgG
    Top Product
    Discover our top product PARP2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))
    别名
    PARP2 (PARP2 产品)
    别名
    ADPRT2 antibody, ADPRTL2 antibody, ADPRTL3 antibody, ARTD2 antibody, PARP-2 antibody, pADPRT-2 antibody, Adprt2 antibody, Adprtl2 antibody, Aspartl2 antibody, C78626 antibody, cb996 antibody, adprtl2 antibody, ADPRT-2 antibody, APP antibody, ATPARP1 antibody, PARP1 antibody, POLY(ADP-RIBOSE) POLYMERASE antibody, POLY(ADP-RIBOSE) POLYMERASE 1 antibody, PP antibody, T14P8.19 antibody, T14P8_19 antibody, poly(ADP-ribose) polymerase antibody, poly(ADP-ribose) polymerase 2 antibody, poly(ADP-ribose) polymerase 2 antibody, poly (ADP-ribose) polymerase family, member 2 antibody, poly (ADP-ribose) polymerase 2 antibody, poly(ADP-ribose) polymerase 2 S homeolog antibody, poly(ADP-ribose) polymerase antibody, PARP2 antibody, Parp2 antibody, parp2 antibody, parp2.S antibody
    背景

    Synonyms: Poly [ADP-ribose] polymerase 2, ADP-ribosyltransferase diphtheria toxin-like 2, NAD(+) ADP-ribosyltransferase 2, Poly[ADP-ribose] synthase 2, PARP-2, hPARP-2, ARTD2, ADPRT-2, pADPRT-2, PARP2, ADPRT2, ADPRTL2

    Background: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. Mainly mediates glutamate and aspartate ADP-ribosylation of target proteins: the ADP-D-ribosyl group of NAD+ is transferred to the acceptor carboxyl group of glutamate and aspartate residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units. ADP-ribosylation follows DNA damage and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Also mediates serine ADP-ribosylation of target proteins following interaction with HPF1, HPF1 conferring serine specificity. In addition to proteins, also able to ADP-ribosylate DNA: preferentially acts on 5'-terminal phosphates at DNA strand breaks termini in nicked duplex

    基因ID
    10038
    UniProt
    Q9UGN5
    途径
    DNA Damage Repair
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