Nesprin3 抗体 (AA 201-300) (Biotin)
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- 抗原 See all Nesprin3 (C14orf49) 抗体
- Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
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抗原表位
- AA 201-300
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Nesprin3 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Nesprin 3
- 亚型
- IgG
- Top Product
- Discover our top product C14orf49 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
- 别名
- Nesprin 3 (C14orf49 产品)
- 别名
- C14orf49 antibody, NET53 antibody, Nesp3 antibody, 4831426I19Rik antibody, nesprin-3 antibody, spectrin repeat containing nuclear envelope family member 3 antibody, spectrin repeat containing, nuclear envelope family member 3 antibody, SYNE3 antibody, Syne3 antibody
- 背景
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Synonyms: C14orf49, Chromosome 14 open reading frame 49, FLJ25605, MGC75267, Nesp3, Nesprin3, Nesprin-3, NET53, Nuclear Envelope Spectrin Repeat Protein 3, Spectrin Repeat Containing, Nuclear Envelope Family Member 3, SYNE3, SYNE3_HUMAN.
Background: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells
- 基因ID
- 161176
- UniProt
- Q6ZMZ3
- 途径
- Maintenance of Protein Location
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