MEIS2 抗体
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- 抗原 See all MEIS2 抗体
- MEIS2 (Meis Homeobox 2 (MEIS2))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This MEIS2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within human MEIS2 aa 1-200
- 克隆位点
- 3C2
- 亚型
- IgG
- Top Product
- Discover our top product MEIS2 Primary Antibody
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- 应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MEIS2 (Meis Homeobox 2 (MEIS2))
- 别名
- MEIS2 (MEIS2 产品)
- 别名
- HsT18361 antibody, MRG1 antibody, A430109D20Rik antibody, Mrg1 antibody, Stra10 antibody, Meis2a.1 antibody, Meis2a.2 antibody, mrg1 antibody, MEIS2 antibody, hst18361 antibody, DKFZp469A1832 antibody, fa26d08 antibody, meis2.2 antibody, wu:fa26d08 antibody, meis2 antibody, meis2.1 antibody, Meis homeobox 2 antibody, Meis homeobox 2 L homeolog antibody, Meis homeobox 2a antibody, Meis homeobox 2b antibody, MEIS2 antibody, Meis2 antibody, meis2.L antibody, meis2 antibody, meis2a antibody, meis2b antibody
- 背景
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Synonyms: Homeobox protein Meis2, Meis1-related protein 1, MEIS2, MRG1
Background: Involved in transcriptional regulation. Binds to HOX or PBX proteins to form dimers, or to a DNA-bound dimer of PBX and HOX proteins and thought to have a role in stabilization of the homeoprotein-DNA complex. Isoform 3 is required for the activity of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element, MEIS2 is not involved in complex DNA-binding. Probably in complex with PBX1, is involved in transcriptional regulation by KLF4. Isoform 3 and isoform 4 can bind to a EPHA8 promoter sequence containing the DNA motif 5'-CGGTCA-3', in cooperation with a PBX protein (such as PBX2) is proposed to be involved in the transcriptional activation of EPHA8 in the developing midbrain. May be involved in regulation of myeloid differentiation. Can bind to the DNA sequence 5'-TGACAG-3'in the activator ACT sequence of the D(1A) dopamine receptor (DRD1) promoter and activate DRD1 transcription, isoform 5 cannot activate DRD1 transcription.
- 基因ID
- 4212
- UniProt
- O14770
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