MADD 抗体 (AA 851-950) (AbBy Fluor® 594)
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- 抗原 See all MADD 抗体
- MADD (MAP-Kinase Activating Death Domain (MADD))
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抗原表位
- AA 851-950
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MADD antibody is conjugated to AbBy Fluor® 594
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应用范围
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DENN
- 亚型
- IgG
- Top Product
- Discover our top product MADD Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MADD (MAP-Kinase Activating Death Domain (MADD))
- 别名
- MADD (MADD 产品)
- 别名
- MADD antibody, MGC145371 antibody, DENN antibody, IG20 antibody, RAB3GEP antibody, 9630059K23Rik antibody, MAP kinase activating death domain antibody, MAP-kinase activating death domain antibody, MADD antibody, madd antibody, Madd antibody
- 背景
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Synonyms: Differentially expressed in normal and neoplastic cells, FLJ35600, IG20, Insulinoma glucagonoma clone 20, KIAA0358, MADD, MADD_HUMAN, MAP kinase-activating death domain protein, Rab3 GDP/GTP exchange factor, RAB3GEP, DENN
Background: Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- 基因ID
- 8567
- UniProt
- Q8WXG6
- 途径
- Caspase Cascade in Apoptosis
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