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KDM4A 抗体

KDM4A 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6943852
发货至: 中国
  • 抗原 See all KDM4A 抗体
    KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This KDM4A antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
    免疫原
    Polyclonal antibody raised in rabbit against human JMJD2a (Jumonji domain containing 2a), using a KLH-conjugated synthetic peptide containing a sequence from the central part of the protein
    Top Product
    Discover our top product KDM4A Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IF()
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.6 μg/μL
    缓冲液
    PBS with 0.05 % sodium azide and 0.05 % Proclin300.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
    别名
    JMJD2a (KDM4A 产品)
    别名
    JMJD2A antibody, JHDM3A antibody, JMJD2 antibody, TDRD14A antibody, D4Ertd222e antibody, Jmjd2 antibody, Jmjd2a antibody, mKIAA0677 antibody, lysine demethylase 4A antibody, lysine-specific demethylase 4A antibody, lysine (K)-specific demethylase 4A antibody, KDM4A antibody, LOC100228023 antibody, Kdm4a antibody
    背景

    Synonyms: JHDM3A, KDM4A, JMJD2, Lysine-specific demethylase 4A

    Background: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively. Isoform 2: Crucial for muscle differentiation, promotes transcriptional activation of the Myog gene by directing the removal of repressive chromatin marks at its promoter. Lacks the N-terminal demethylase domain.

    基因ID
    9682
    UniProt
    O75164
    途径
    Warburg Effect
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