KDM4A 抗体
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- 抗原 See all KDM4A 抗体
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KDM4A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
- 免疫原
- Polyclonal antibody raised in rabbit against human JMJD2a (Jumonji domain containing 2a), using a KLH-conjugated synthetic peptide containing a sequence from the central part of the protein
- Top Product
- Discover our top product KDM4A Primary Antibody
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anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 141-310) antibody
KDM4A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 932-1057) antibodyKDM4A 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 6E10G4 unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 585-815) antibodyKDM4A 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) antibodyKDM4A 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 5H1 unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 127-364) antibodyKDM4A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) antibodyKDM4A 适用: 人 DB, ICC 宿主: 小鼠 Monoclonal 3559D5a unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (Center) antibodyKDM4A 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IF() - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.6 μg/μL
- 缓冲液
- PBS with 0.05 % sodium azide and 0.05 % Proclin300.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
- 别名
- JMJD2a (KDM4A 产品)
- 别名
- JMJD2A antibody, JHDM3A antibody, JMJD2 antibody, TDRD14A antibody, D4Ertd222e antibody, Jmjd2 antibody, Jmjd2a antibody, mKIAA0677 antibody, lysine demethylase 4A antibody, lysine-specific demethylase 4A antibody, lysine (K)-specific demethylase 4A antibody, KDM4A antibody, LOC100228023 antibody, Kdm4a antibody
- 背景
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Synonyms: JHDM3A, KDM4A, JMJD2, Lysine-specific demethylase 4A
Background: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively. Isoform 2: Crucial for muscle differentiation, promotes transcriptional activation of the Myog gene by directing the removal of repressive chromatin marks at its promoter. Lacks the N-terminal demethylase domain.
- 基因ID
- 9682
- UniProt
- O75164
- 途径
- Warburg Effect
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