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Integrin beta 4 抗体

ITGB4 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Monoclonal 6C1 unconjugated
产品编号 ABIN6943811
发货至: 中国
  • 抗原 See all Integrin beta 4 (ITGB4) 抗体
    Integrin beta 4 (ITGB4)
    适用
    • 80
    • 25
    • 24
    • 3
    • 3
    人, 小鼠
    宿主
    • 55
    • 34
    • 10
    • 2
    克隆类型
    • 51
    • 50
    单克隆
    标记
    • 52
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    This Integrin beta 4 antibody is un-conjugated
    应用范围
    • 50
    • 43
    • 30
    • 30
    • 19
    • 15
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    • 13
    • 9
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Human Integrin beta 4 between 1750-1850 amino acids
    克隆位点
    6C1
    亚型
    IgG
    Top Product
    Discover our top product ITGB4 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC()
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    Integrin beta 4 (ITGB4)
    别名
    Integrin beta 4 (ITGB4 产品)
    别名
    AA407042 antibody, C230078O20 antibody, CD104 antibody, integrin subunit beta 4 antibody, integrin beta 4 antibody, ITGB4 antibody, Itgb4 antibody
    背景

    Synonyms: Integrin beta-4, GP150, CD104, ITGB4

    Background: Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464).

    UniProt
    P16144
    途径
    Integrin Complex
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