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EXOSC4 抗体 (AA 51-150) (AbBy Fluor® 488)

EXOSC4 适用: 小鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 488
产品编号 ABIN6943362
发货至: 中国
  • 抗原 See all EXOSC4 抗体
    EXOSC4 (Exosome Component 4 (EXOSC4))
    抗原表位
    • 14
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 51-150
    适用
    • 29
    • 21
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 40
    • 3
    克隆类型
    • 41
    • 2
    多克隆
    标记
    • 20
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EXOSC4 antibody is conjugated to AbBy Fluor® 488
    应用范围
    • 27
    • 22
    • 12
    • 12
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Dog,Cow,Sheep,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human EXOSC4
    亚型
    IgG
    Top Product
    Discover our top product EXOSC4 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    EXOSC4 (Exosome Component 4 (EXOSC4))
    别名
    EXOSC4 (EXOSC4 产品)
    别名
    EXOSC4 antibody, zgc:73175 antibody, RRP41 antibody, RRP41A antibody, Rrp41p antibody, SKI6 antibody, Ski6p antibody, hRrp41p antibody, p12A antibody, 1110039I09Rik antibody, 1500001N04Rik antibody, Rrp41 antibody, exosome component 4 antibody, exosome component 4 S homeolog antibody, exosc4 antibody, EXOSC4 antibody, CC1G_03561 antibody, exosc4.S antibody, Exosc4 antibody
    背景

    Synonyms: EXOSC 4, Exosome complex component RRP41, Exosome complex exonuclease RRP41, Exosome component 4, Exosome component Rrp41, FLJ20591, hRrp41p, p12A, EXOS4_HUMAN, Ribosomal RNA processing protein 41, RRP 41, RRP41, RRP41A, Rrp41p, SKI 6, SKI6, Ski6p.

    Background: The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3 to 5 exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3 region. EXOSC4 (exosome component 4), also known as SKI6, RRP41 or p12A, is a 245 amino acid protein that localizes to both the nucleus and the cytoplasm and shares 96 % sequence identity with its mouse counterpart. Functioning as a component of the exosome complex, EXOSC4 exhibits 3'-5' exonuclease activity and is required for the 3'-processing of 7S pre-RNA to mature 5.8S rRNA. The gene encoding EXOSC4 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.

    基因ID
    54512
    UniProt
    Q9NPD3
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