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Envoplakin-Like 抗体 (AA 101-200) (Cy5)

EVPLL 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN6943324
发货至: 中国
  • 抗原 See all Envoplakin-Like (EVPLL) products
    Envoplakin-Like (EVPLL)
    抗原表位
    • 14
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    AA 101-200
    适用
    宿主
    • 29
    克隆类型
    • 29
    多克隆
    标记
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Envoplakin-Like antibody is conjugated to Cy5
    应用范围
    • 15
    • 15
    • 12
    • 12
    • 12
    • 5
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human EVPLL
    亚型
    IgG
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Envoplakin-Like (EVPLL)
    别名
    EVPLL (EVPLL 产品)
    别名
    envoplakin like antibody, EVPLL antibody
    背景

    Synonyms: Envoplakin like, Envoplakin-like protein, EVPLL, EVPLL_HUMAN,

    Background: EVPLL (envoplakin-like protein) is a 301 amino acid protein that belongs to the plakin or cytolinker family. The gene encoding EVPLL maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

    基因ID
    645027
    UniProt
    A8MZ36
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