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DEPTOR 抗体 (AA 151-250) (Biotin)

DEPTOR 适用: 人, 小鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN6942875
发货至: 中国
  • 抗原 See all DEPTOR 抗体
    DEPTOR (DEP Domain Containing mTOR-Interacting Protein (DEPTOR))
    抗原表位
    • 15
    • 14
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    适用
    • 51
    • 33
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 46
    • 4
    • 1
    克隆类型
    • 49
    • 2
    多克隆
    标记
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DEPTOR antibody is conjugated to Biotin
    应用范围
    • 43
    • 26
    • 26
    • 9
    • 7
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human DEPTOR
    亚型
    IgG
    Top Product
    Discover our top product DEPTOR Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    DEPTOR (DEP Domain Containing mTOR-Interacting Protein (DEPTOR))
    别名
    DEPTOR (DEPTOR 产品)
    别名
    DEP.6 antibody, DEPDC6 antibody, 4731402B04Rik antibody, 9130412E02Rik antibody, D15Ertd336e antibody, D15Ertd597e antibody, Depdc6 antibody, Depdc6-001 antibody, Depdc6-002 antibody, R75183 antibody, mKIAA4200 antibody, RGD1561030 antibody, RAPGEF4 antibody, DEP domain containing MTOR interacting protein antibody, DEP domain containing MTOR-interacting protein antibody, DEPTOR antibody, Deptor antibody
    背景

    Synonyms: DEP domain containing 6, DEP domain-containing mTOR-interacting protein, DEP domain-containing protein 6, DEPDC6, DEPTOR, DPTOR_HUMAN.

    Background: DEPTOR (DEP domain containing MTOR-interacting protein), also known as DEP.6 or DEPDC6 (DEP domain-containing protein 6), is a 409 amino acid protein that negatively regulates mTORC1 and mTORC2 pathways. DEPTOR interacts with FRAP via its PDZ domain, and undergoes post-translational phosphorylation. Containing two DEP domains and one PDZ (DHR) domain, DEPTOR is encoded by a gene that maps to human chromosome 8q24.12. Chromosome 8 consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

    基因ID
    64798
    UniProt
    Q8TB45
    途径
    PI3K-Akt Signaling, RTK signaling, Regulation of Cell Size, BCR Signaling, Warburg Effect
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