DENND1A 抗体 (AA 42-140) (Biotin)
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- 抗原 See all DENND1A 抗体
- DENND1A (DENN/MADD Domain Containing 1A (DENND1A))
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抗原表位
- AA 42-140
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DENND1A antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DENND1A
- 亚型
- IgG
- Top Product
- Discover our top product DENND1A Primary Antibody
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- DENND1A (DENN/MADD Domain Containing 1A (DENND1A))
- 别名
- DENND1A (DENND1A 产品)
- 别名
- RGD1307927 antibody, FAM31A antibody, KIAA1608 antibody, RP11-230L22.3 antibody, 6030446I19Rik antibody, connecdenn antibody, fam31a antibody, DENN domain containing 1A antibody, DENN/MADD domain containing 1A antibody, DENN domain-containing protein 1A antibody, DENN domain containing 1A S homeolog antibody, Dennd1a antibody, DENND1A antibody, dennd1a antibody, LOC100512328 antibody, dennd1a.S antibody
- 背景
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Synonyms: Connecdenn 1, Connecdenn, DEN1A_HUMAN, DENN domain-containing protein 1A, DENN/MADD domain containing 1A, dennd1a, FAM31A, FLJ21129, FLJ38464, KIAA1608, OTTHUMP00000022090, Protein FAM31A, RP11 230L22.3.
Background: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010]
- 基因ID
- 57706
- UniProt
- Q8TEH3
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