电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CMA1 抗体

CMA1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Monoclonal 1G11 unconjugated
产品编号 ABIN6942587
发货至: 中国
  • 抗原 See all CMA1 抗体
    CMA1 (Chymase 1, Mast Cell (CMA1))
    适用
    • 32
    • 21
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 41
    • 9
    • 1
    • 1
    克隆类型
    • 36
    • 16
    单克隆
    标记
    • 26
    • 9
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CMA1 antibody is un-conjugated
    应用范围
    • 29
    • 21
    • 18
    • 9
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant protein within human Mast Cell Chymase aa 50-200
    克隆位点
    1G11
    亚型
    IgG
    Top Product
    Discover our top product CMA1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CMA1 (Chymase 1, Mast Cell (CMA1))
    别名
    CMA1 (CMA1 产品)
    别名
    CYH antibody, MCT1 antibody, chymase antibody, MMCP-5 antibody, Mcp-5 antibody, Mcp5 antibody, Mcpt5 antibody, MCP3P antibody, CMA1 antibody, Chymase antibody, chymase 1 antibody, chymase 1, mast cell antibody, chymase-like antibody, CMA1 antibody, Cma1 antibody, LOC100008644 antibody
    背景

    Synonyms: Chymase 1, Alpha-chymase, Mast cell protease I, CMA1, CYH, CYM.

    Background: Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Mast Cell Chymase, also known as CMA1 or MCT1, is a major secreted serine protease that is involved in vasoactive peptide generation, extracellular matrix degradation and regulation of gland secretion. The human chymase gene, which maps to human chromosome 14q11.2, encodes a preproenzyme with a 19 amino acid signal peptide, an acidic 2 amino acid propeptide and a 226 amino acid catalytic domain. Mast Cell Chymase is a chymotryptic serine proteinase which is a member of the peptidase family S1. Expressed in mast cells, Mast Cell Chymase is associated with the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. Mast cell proteases are a family of rodent protein homologs to human tryptases that are specifically expressed in mast cells and may serve as highly specific markers in the analysis of mast cell heterogeneity, differentiation and function.

    基因ID
    1215
    UniProt
    P23946
    途径
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
You are here:
客服