ADAP2 抗体 (AA 201-300) (Biotin)
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- 抗原 See all ADAP2 抗体
- ADAP2 (ArfGAP with Dual PH Domains 2 (ADAP2))
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抗原表位
- AA 201-300
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADAP2 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Possible cross-reactivity with ADAP1 (85 % homology with the immunogen sequence, 43 kDa)
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Centaurin alpha 2
- 亚型
- IgG
- Top Product
- Discover our top product ADAP2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- ADAP2 (ArfGAP with Dual PH Domains 2 (ADAP2))
- 别名
- Centaurin alpha 2 (ADAP2 产品)
- 别名
- CENTA2 antibody, HSA272195 antibody, cent-b antibody, Centa2 antibody, ArfGAP with dual PH domains 2 antibody, ADAP2 antibody, Adap2 antibody
- 背景
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Synonyms: ADAP2, ADAP2_HUMAN, Arf-GAP with dual PH domain-containing protein 2, ArfGAP with dual PH domains 2, cent b, Centa 2, CENTA2, Centaurin alpha 2, Centaurin alpha 2 protein, Centaurin beta, Centaurin-alpha-2, Cnt-a2, HSA272195.
Background: The ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organization and cell adhesion. The Centaurin GTPase-activating protein family comprise a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of ARF-dependent pathways. This family includes ASAP1, ACAP1, ACAP2, AGAP1, ARAP1, ARAP2, Centaurin a1, Centaurin g3 and the recently discovered Centaurin a2. Expressed in a wide variety of tissues such as fat, heart and skeletal muscle, Centaurin a2 is thought to negatively regulate ARF-mediated actin rearrangement by binding activated PI 3-kinase. Although the exact function of Centaurin a2 is not yet known, its high sequence similarity with Centaurin a1 suggests that it may also act as an ARF6 GTPase.
- 基因ID
- 55803
- UniProt
- Q9NPF8
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