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CD81 抗体

CD81 适用: 人, 小鼠, 大鼠 FACS, WB, IHC, IF, Func, StM 宿主: 小鼠 Monoclonal 1-3-3-22 unconjugated
产品编号 ABIN6941280
发货至: 中国
  • 抗原 See all CD81 抗体
    CD81
    适用
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    人, 小鼠, 大鼠
    宿主
    • 68
    • 61
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    • 1
    小鼠
    克隆类型
    • 121
    • 47
    • 3
    单克隆
    标记
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    This CD81 antibody is un-conjugated
    应用范围
    • 123
    • 78
    • 43
    • 38
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    • 27
    • 27
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Functional Studies (Func), Staining Methods (StM)
    特异性
    Recognizes a protein of 26 kDa, identified as CD81 (Workshop VI, Code CD81.1)). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.
    纯化方法
    Purified by Protein A/G
    免疫原
    B-Cell line derived from a Burkitt lymphoma
    克隆位点
    1-3-3-22
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD81 Primary Antibody
  • 应用备注

    Positive Control: Ramos, Daudi, Raji, U266, HUT-78, HUT-102, Jurkat, HL-60, KG1a, A293, A431, MG63 and human lymphocytes. Tonsil or Liver.

    Known Application: Functional Studies (Order Ab without Azide),Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Western Blot (0.5-1.0 μg/mL for 2 hours at RT),Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD81
    别名
    CD81 (CD81 产品)
    别名
    Tapa-1 antibody, Tapa1 antibody, Tspan28 antibody, CVID6 antibody, S5.7 antibody, TAPA1 antibody, TSPAN28 antibody, CD81 molecule antibody, CD81 molecule b antibody, CD81 antigen antibody, Cd81 molecule antibody, CD81 antibody, cd81b antibody, Cd81 antibody
    分子量
    26kDa
    基因ID
    975
    UniProt
    P60033
    途径
    Inositol Metabolic Process, Hepatitis C
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