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- 抗原 See all MUC16 (CA125) 抗体
- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MUC16 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Full length native MUC16 protein Purified from human ovarian carcinoma
- 克隆位点
- MUC16-1860
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CA125 Primary Antibody
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anti-Mucin 16, Cell Surface Associated (CA125) (AA 1-200) antibody
CA125 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4C8C8 unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 13977-14117) antibodyCA125 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) antibodyCA125 适用: 人 IHC, StM 宿主: 兔 Monoclonal OCA125-2349R unconjugated Recombinant Antibody
anti-Mucin 16, Cell Surface Associated (CA125) (AA 250-350) antibodyCA125 适用: 人 ELISA, WB, IHC (p), FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 2-258) antibodyCA125 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 14067-14328) antibodyCA125 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) antibodyCA125 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 10329-10628) antibodyCA125 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-Mucin 16, Cell Surface Associated (CA125) (AA 10329-10628) antibodyCA125 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3B6 unconjugated
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- 应用备注
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Positive Control: MDA-MB-468 cells. Ovarian Cancer.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
- 别名
- CA125 (CA125 产品)
- 别名
- CA125 antibody, 1110008I14Rik antibody, Ca125 antibody, Gm1480 antibody, RGD1308422 antibody, MUC16 antibody, mucin 16, cell surface associated antibody, mucin 16 antibody, mucin-16 antibody, MUC16 antibody, Muc16 antibody, LOC476718 antibody, LOC712735 antibody
- 背景
- The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.
- 分子量
- >2,000kDa
- 基因ID
- 94025
- UniProt
- Q8WXI7
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