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CD22 抗体

CD22 适用: 人, 小鼠, 大鼠 FACS, IM 宿主: 小鼠 Monoclonal MYG13 unconjugated
产品编号 ABIN6941118
发货至: 中国
  • 抗原 See all CD22 抗体
    CD22 (CD22 Molecule (CD22))
    适用
    • 138
    • 49
    • 23
    • 5
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 85
    • 62
    • 15
    小鼠
    克隆类型
    • 109
    • 55
    单克隆
    标记
    • 82
    • 14
    • 13
    • 10
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD22 antibody is un-conjugated
    应用范围
    • 98
    • 72
    • 44
    • 37
    • 35
    • 18
    • 12
    • 12
    • 11
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
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    • 1
    • 1
    Flow Cytometry (FACS), Immunomicroscopy (IM)
    特异性
    Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.
    纯化方法
    Purified by Protein A/G
    免疫原
    Human Raji cells
    克隆位点
    MYG13
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD22 Primary Antibody
  • 应用备注

    Positive Control: Ramos, Raji, Daudi, IM9, JY25 and human peripheral blood lymphocytes. Human tonsil and lymphocytes.

    Known Application: Flow Cytometry (0.5-1 μg/million cells),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD22 (CD22 Molecule (CD22))
    别名
    CD22 (CD22 产品)
    别名
    A530093D23 antibody, Lyb-8 antibody, Lyb8 antibody, SIGLEC-2 antibody, SIGLEC2 antibody, siglec-2 antibody, CD22 antigen antibody, CD22 molecule antibody, Cd22 antibody, CD22 antibody
    分子量
    130-140kDa
    基因ID
    933
    UniProt
    P20273
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