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CD3 epsilon 抗体

CD3E 适用: 人, 猴 FACS, IF, Act, ProA 宿主: 小鼠 Monoclonal CRIS-7 unconjugated
产品编号 ABIN6941029
发货至: 中国
  • 抗原 See all CD3 epsilon (CD3E) 抗体
    CD3 epsilon (CD3E)
    适用
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    人, 猴
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD3 epsilon antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), Activation (Act), Proliferation Assay (ProA)
    特异性
    Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
    免疫原
    Stimulated human leukocytes
    克隆位点
    CRIS-7
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD3E Primary Antibody
  • 应用备注

    Positive Control: Jurkat cells. Tonsil and lymph node.

    Known Application: Induce T cell activation and proliferation (Order Ab without Azide),Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD3 epsilon (CD3E)
    别名
    CD3E (CD3E 产品)
    分子量
    20kDa
    基因ID
    916
    UniProt
    P07766
    途径
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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