PDLIM1 抗体
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- 抗原 See all PDLIM1 抗体
- PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PDLIM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant human full-length PDLIM1 protein
- 克隆位点
- CPTC-PDLIM1-1
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product PDLIM1 Primary Antibody
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- 应用备注
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Positive Control: HepG2 cells and extracts from Jurkat. Human heart, colon or spleen.
Known Application: Western Blot (0.5-1.0 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- PDLIM1 (PDZ and LIM Domain 1 (PDLIM1))
- 别名
- PDLIM1 (PDLIM1 产品)
- 别名
- CLIM1 antibody, CLP-36 antibody, CLP36 antibody, hCLIM1 antibody, pdlim1 antibody, MGC76041 antibody, MGC64465 antibody, clim1 antibody, wu:fa19a03 antibody, wu:fy34f10 antibody, zgc:110681 antibody, Clim1 antibody, mClim1 antibody, PDLIM1 antibody, PDZ and LIM domain 1 antibody, PDZ and LIM domain 1 L homeolog antibody, PDZ and LIM domain 1 (elfin) antibody, PDLIM1 antibody, Pdlim1 antibody, pdlim1 antibody, pdlim1.L antibody
- 背景
- CLP36, also known as PDLIM1, CLIM1 or Elfin, is a 329 amino acid cytoplasmic protein that associates with actin stress fibers at the cytoskeleton. Expressed at high levels in skeletal muscle and heart and at lower levels in colon, small intestine, spleen, lung, placenta, kidney, liver, thymus and pancreas, CLP36 functions as a cytoskeletal protein that is thought to act as an adaptor, bringing target proteins to the cytoskeleton. Specifically, CLP36 interacts with Clik1 (-actinin-1, thereby facilitating the association of Clik1 with actin stress fibers. CLP36 contains one PDZ domain and one LIM zinc-binding domain through which it conveys its protein-protein binding capabilities. Human CLP36 shares 88 % sequence similarity with its rat counterpart, suggesting a conserved function between species.
- 分子量
- 36kDa
- 基因ID
- 9124
- UniProt
- O00151
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