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CD1c 抗体

CD1C 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal CD1C-1603 unconjugated
产品编号 ABIN6941008
发货至: 中国
  • 抗原 See all CD1c (CD1C) 抗体
    CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))
    适用
    • 40
    • 3
    • 3
    • 1
    • 1
    宿主
    • 22
    • 17
    • 1
    小鼠
    克隆类型
    • 24
    • 16
    单克隆
    标记
    • 23
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    This CD1c antibody is un-conjugated
    应用范围
    • 23
    • 22
    • 11
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Coating (Coat)
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant full-length human CD1c protein
    克隆位点
    CD1C-1603
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD1C Primary Antibody
  • 应用备注

    Positive Control: Expressed on cortical thymocytes, on certain T-cell leukemias and in various other tissues.

    Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))
    别名
    CD1C (CD1C 产品)
    背景
    The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with -2-Microglobulin and expressed on cortical thymocytes, Langerhans cells, a B cell subset and some dendritic cells. Specifically, CD1A is a marker for Langerhans cell histiocytosis (LCH) and is found on interdigitating cells. Adaptor-protein complexes and CD1-associated chaperones control CD1 trafficking, and the development and activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. The human CD1 genes are all closely linked in a cluster mapping at chromosome 1q23.1
    分子量
    43kDa
    基因ID
    911
    UniProt
    P29017
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