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CD1a 抗体

CD1a 适用: 人 FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal SPM120 unconjugated
产品编号 ABIN6940997
发货至: 中国
  • 抗原 See all CD1a 抗体
    CD1a
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD1a antibody is un-conjugated
    应用范围
    • 99
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    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Staining Methods (StM)
    纯化方法
    Purified by Protein A/G
    免疫原
    Human thymus cells
    克隆位点
    SPM120
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD1a Primary Antibody
  • 应用备注

    Positive Control: Jurkat, MOLT-4 cells. Paracortex in a tonsil or a reactive lymph node.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD1a
    别名
    CD1A (CD1a 产品)
    别名
    CD1 antibody, FCB6 antibody, HTA1 antibody, R4 antibody, T6 antibody, CD1A antibody, CD1a molecule antibody, CD1 antigen antibody, T-cell surface glycoprotein CD1a antibody, CD1A antibody, CD1.1 antibody, LOC100156095 antibody, LOC101111409 antibody
    背景
    At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).
    分子量
    49kDa
    基因ID
    909
    UniProt
    P06126
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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