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ACTN2 抗体 (AA 557-692)

ACTN2 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ACTN2-3293 unconjugated
产品编号 ABIN6940980
发货至: 中国
  • 抗原 See all ACTN2 抗体
    ACTN2 (Actinin, alpha 2 (ACTN2))
    抗原表位
    • 15
    • 14
    • 9
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 557-692
    适用
    • 63
    • 50
    • 35
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    宿主
    • 74
    • 10
    小鼠
    克隆类型
    • 65
    • 19
    单克隆
    标记
    • 40
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACTN2 antibody is un-conjugated
    应用范围
    • 65
    • 21
    • 20
    • 14
    • 13
    • 12
    • 10
    • 10
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
    纯化方法
    Purified by Protein A/G
    免疫原
    A recombinant fragment (aa557-692) of human ACTN2 protein (exact sequence is proprietary)
    克隆位点
    ACTN2-3293
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ACTN2 Primary Antibody
  • 应用备注

    Positive Control: Skeletal or Cardiac Muscle.

    Known Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    ACTN2 (Actinin, alpha 2 (ACTN2))
    别名
    ACTN2 (ACTN2 产品)
    别名
    MGC89234 antibody, ACTN2 antibody, 1110008F24Rik antibody, CMD1AA antibody, wu:fd44c03 antibody, zgc:123223 antibody, actinin alpha 2 antibody, actinin, alpha 2b antibody, actinin alpha 2 S homeolog antibody, actn2 antibody, ACTN2 antibody, Actn2 antibody, actn2b antibody, actn2.S antibody
    背景
    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
    分子量
    103kDa
    基因ID
    88
    UniProt
    P35609
    途径
    Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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