p63 抗体 (AA 5-17)
-
- 抗原 See all p63 (TP63) 抗体
- p63 (TP63) (Tumor Protein P63 (TP63))
-
抗原表位
- AA 5-17
-
适用
- 人, 小鼠, 大鼠, Cow
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This p63 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
- 免疫原
- A synthetic peptide (ENNAQTQFSEPQY) corresponding to aa5-17 of human p40
- 亚型
- IgG
- Top Product
- Discover our top product TP63 Primary Antibody
-
-
- 应用备注
-
Positive Control: HEK293 cells. Prostate Carcinoma or Lung Squamous Cell Carcinoma.
Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
-
- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
-
- 抗原
- p63 (TP63) (Tumor Protein P63 (TP63))
- 别名
- TP63 (TP63 产品)
- 背景
- P40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p63 antibody's ability to distinguish between the tumor types appears to be inferior when compared to p40. The ability to utilize an antibody probe for p40 as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques.
- 分子量
- 40kDa
- 基因ID
- 8626
- UniProt
- Q9H3D4
-