BAP1 抗体 (AA 191-326)
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- 抗原 See all BAP1 抗体
- BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))
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抗原表位
- AA 191-326
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BAP1 antibody is un-conjugated
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应用范围
- ELISA, Coating (Coat)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant human BAP1 protein fragment (around aa 191-326) (exact sequence is proprietary)
- 克隆位点
- BAP1-2431
- 亚型
- IgG2c kappa
- Top Product
- Discover our top product BAP1 Primary Antibody
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- 应用备注
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Positive Control: Jurkat or PC-3 or HepG2 cells. Testis, Placenta, Ovarian or Breast Carcinoma.
Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))
- 别名
- BAP1 (BAP1 产品)
- 别名
- HUCEP-13 antibody, UCHL2 antibody, BAIAP3 antibody, 2300006C11Rik antibody, AA989761 antibody, AW553466 antibody, mKIAA0272 antibody, uch-x4 antibody, hucep-13 antibody, hucep-6 antibody, uchl2 antibody, si:dkey-42i9.9 antibody, BRCA1 associated protein 1 antibody, Brca1 associated protein 1 antibody, BRCA1 associated protein 1 L homeolog antibody, BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) antibody, BAP1 antibody, Bap1 antibody, bap1.L antibody, bap1 antibody
- 背景
- The BAP1 gene belongs to the ubiquitin C-terminal hydrolase subfamily of de-ubiquitination enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germ line mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, Uveal melanoma and cutaneous melanoma.
- 分子量
- 91kDa
- 基因ID
- 8314
- UniProt
- Q92560
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