PAX8 抗体 (AA 60-261)
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- 抗原 See all PAX8 抗体
- PAX8 (Paired Box 8 (PAX8))
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抗原表位
- AA 60-261
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PAX8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
- 特异性
- Recognizes a protein of 62 kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant fragment (around aa 60-261) of human PAX8 protein (exact sequence is proprietary)
- 克隆位点
- PAX8-1491
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product PAX8 Primary Antibody
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anti-Paired Box 8 (PAX8) antibody
KO Validated PAX8 适用: 人 WB, IHC, IF, IHC (p), IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 8 (PAX8) (AA 60-261) antibodyPAX8 适用: 人 WB, IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal PAX8-1492 unconjugated
anti-Paired Box 8 (PAX8) (AA 60-261) antibodyPAX8 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1A1D3 unconjugated
anti-Paired Box 8 (PAX8) (AA 1-450) antibodyPAX8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H7 unconjugated
anti-Paired Box 8 (PAX8) (AA 141-250) antibodyPAX8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Paired Box 8 (PAX8) (AA 300-377) antibodyPAX8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G11 unconjugated
anti-Paired Box 8 (PAX8) (AA 300-377) antibodyPAX8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D6 unconjugated
anti-Paired Box 8 (PAX8) (N-Term) antibodyVerified PAX8 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Paired Box 8 (PAX8) (AA 300-450) antibodyPAX8 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3E6B3 unconjugated
anti-Paired Box 8 (PAX8) (AA 285-313) antibodyPAX8 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Positive Control: Raji cells. Renal Cell Carcinoma (RCC).
Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- PAX8 (Paired Box 8 (PAX8))
- 别名
- PAX8 (PAX8 产品)
- 分子量
- 62kDa
- 基因ID
- 7849
- UniProt
- Q06710
- 途径
- Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
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