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YWHAE 抗体

YWHAE 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal CPTC-YWHAE-1 unconjugated
产品编号 ABIN6940908
发货至: 中国
  • 抗原 See all YWHAE 抗体
    YWHAE (14-3-3 epsilon (YWHAE))
    适用
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    宿主
    • 54
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    小鼠
    克隆类型
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    单克隆
    标记
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    This YWHAE antibody is un-conjugated
    应用范围
    • 41
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    Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant human full-length YWHAE protein
    克隆位点
    CPTC-YWHAE-1
    亚型
    IgG2a kappa
    Top Product
    Discover our top product YWHAE Primary Antibody
  • 应用备注

    Positive Control: HEK-293 or A-431 cell lines.

    Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    YWHAE (14-3-3 epsilon (YWHAE))
    别名
    YWHAE (YWHAE 产品)
    背景
    Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.
    分子量
    29.4kDa
    基因ID
    7531
    UniProt
    P62268
    途径
    Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
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