Ubiquitin B 抗体 (AA 1-119)
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- 抗原 See all Ubiquitin B (UBB) 抗体
- Ubiquitin B (UBB)
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抗原表位
- AA 1-119
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Ubiquitin B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant fragment of human Ubiquitin protein (around aa 1-119) (exact sequence is proprietary)
- 克隆位点
- UBB-1748
- 亚型
- IgG2c kappa
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anti-Ubiquitin B (UBB) (AA 1-119) antibody
UBB 适用: 人 WB, IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal UBB-2122 unconjugated
anti-Ubiquitin B (UBB) antibodyUBB 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3C12 unconjugated
anti-Ubiquitin B (UBB) antibodyUBB 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Ubiquitin B (UBB) (AA 1-76) antibodyUBB 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F5 unconjugated
anti-Ubiquitin B (UBB) (AA 1-76) antibodyUBB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin B (UBB) (AA 77-152) antibodyUBB 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin B (UBB) (AA 103-228) antibodyUBB 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin B (UBB) (AA 1-119) antibodyUBB 适用: 人 IHC, StM 宿主: 兔 Monoclonal UBB-3143R unconjugated Recombinant Antibody
anti-Ubiquitin B (UBB) antibodyUBB 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Ubiquitin B (UBB) (AA 25-57), (N-Term) antibodyUBB 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB49507 unconjugated
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- 应用备注
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Positive Control: MCF-7, HeLa or Jurkat cells. Alzheimer's Brain.
Known Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- Ubiquitin B (UBB)
- 别名
- UBB (UBB 产品)
- 别名
- AL033289 antibody, Rps27a antibody, Uba52 antibody, Ubb2 antibody, Ubc antibody, UBC antibody, Ubiquitin antibody, UBB antibody, Ubi-p63E antibody, im:6892314 antibody, si:ch211-202a12.3 antibody, ubc antibody, zUBC antibody, zgc:172187 antibody, ubiquitin B antibody, ubiquitin C antibody, UBB antibody, Ubb antibody, UBC antibody, ubb antibody
- 背景
- Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease etc.
- 分子量
- 9kDa
- 基因ID
- 7314
- UniProt
- P62979, P62987, P62988
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, Autophagy, EGFR Downregulation, Ubiquitin Proteasome Pathway
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