Tyrosinase-Related Protein 1 抗体 (AA 257-377)
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- 抗原 See all Tyrosinase-Related Protein 1 (TYRP1) 抗体
- Tyrosinase-Related Protein 1 (TYRP1)
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抗原表位
- AA 257-377
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Tyrosinase-Related Protein 1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Staining Methods (StM), Coating (Coat)
- 特异性
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- A recombinant fragment (around aa 257-377) of human TYRP1 protein (exact sequence is proprietary)
- 克隆位点
- TYRP1-3280
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product TYRP1 Primary Antibody
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- 应用备注
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Positive Control: SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells. Human skin or melanoma tissues (IHC).
Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- Tyrosinase-Related Protein 1 (TYRP1)
- 别名
- TYRP1 (TYRP1 产品)
- 别名
- CAS2 antibody, CATB antibody, GP75 antibody, OCA3 antibody, TRP antibody, TRP1 antibody, TYRP antibody, b-PROTEIN antibody, LOC397853 antibody, Trypsin antibody, hm:zeh0659 antibody, tyrp1 antibody, zgc:100893 antibody, B antibody, TYRP1 antibody, tyrp-1 antibody, TRP-1 antibody, Tyrp antibody, b antibody, brown antibody, isa antibody, tyrosinase related protein 1 antibody, protease, serine 1 L homeolog antibody, tyrosinase-related protein 1b antibody, tyrosinase-related protein 1 antibody, tyrosinase-related protein 1 L homeolog antibody, tyrosinase-related protein 1a antibody, TYRP1 antibody, prss1.L antibody, tyrp1b antibody, Tyrp1 antibody, tyrp1.L antibody, tyrp1 antibody, LOC100136490 antibody, tyrp-1 antibody, tyrp1a antibody
- 分子量
- 75kDa
- 基因ID
- 7306
- UniProt
- P17643
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