TSHB 抗体
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- 抗原 See all TSHB 抗体
- TSHB (Thyroid Stimulating Hormone, beta (TSHB))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TSHB antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunostaining (ISt), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant human TSH beta fragment
- 克隆位点
- TSHb-1317
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TSHB Primary Antibody
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- 应用备注
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Positive Control: Normal pituitary or its tumor.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- TSHB (Thyroid Stimulating Hormone, beta (TSHB))
- 别名
- TSHB (TSHB 产品)
- 别名
- TSH-B antibody, TSH-BETA antibody, TSHB antibody, thyroid stimulating hormone beta antibody, thyroid stimulating hormone, beta antibody, thyroid stimulating hormone, beta subunit antibody, TSHB antibody, Tshb antibody, tshb antibody
- 背景
- The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH) follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
- 分子量
- 16kDa
- 基因ID
- 7252
- UniProt
- P01222
- 途径
- Thyroid Hormone Synthesis, Peptide Hormone Metabolism
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