TPSAB1 抗体 (AA 115-233)
-
- 抗原 See all TPSAB1 抗体
- TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
-
抗原表位
- AA 115-233
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This TPSAB1 antibody is un-conjugated
-
应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 特异性
- Tryptases comprise a family of trypsin-like serine proteases (peptidase family S1). Tryptases are stored in mast cell secretory granules and basophils. Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Tryptases are released into the extracellular environment and are resistant to all known endogenous proteinase inhibitors. This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant human Tryptase protein fragment (around aa 115-233) (Exact sequence is proprietary)
- 克隆位点
- TPSAB1-1961
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TPSAB1 Primary Antibody
-
-
- 应用备注
-
Positive Control: Skin or Tonsil.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
-
- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
-
- 抗原
- TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))
- 别名
- TPSAB1 (TPSAB1 产品)
- 别名
- TPS1 antibody, TPS2 antibody, TPSB1 antibody, PMCT7 antibody, tpsab1 antibody, tryptaseB antibody, tryptaseC antibody, MMCP-7 antibody, Mcp-7 antibody, Mcp7 antibody, Mcpt7 antibody, rMCP-7 antibody, AV011504 antibody, MMCP-6 antibody, Mcp-6 antibody, Mcp6 antibody, Mcpt6 antibody, tryptase alpha/beta 1 antibody, tryptase antibody, tryptase beta 2 (gene/pseudogene) antibody, tryptase beta 2 antibody, TPSAB1 antibody, MCT7 antibody, tpsab1 antibody, TPSB2 antibody, Tpsab1 antibody, Tpsb2 antibody
- 分子量
- 31-36kDa
- 基因ID
- 7177
- UniProt
- Q15661
-