NKX2-1 抗体
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- 抗原 See all NKX2-1 抗体
- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NKX2-1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Staining Methods (StM)
- 特异性
- Recognizes a protein of 40 kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
- 交叉反应 （详细）
- Shows a broad species reactivity.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Rat full length TTF-1 recombinant protein
- 克隆位点
- 8G7G3-1
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product NKX2-1 Primary Antibody
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anti-NK2 Homeobox 1 (NKX2-1) antibody
NKX2-1 适用: 人 WB, IF, IHC 宿主: 兔 Monoclonal unconjugated
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人 WB, FACS, ELISA, IHC 宿主: 兔 Monoclonal 6C11 unconjugated Recombinant Antibody
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人, 小鼠, 大鼠 IHC, StM 宿主: 兔 Monoclonal NX2-1-1855R unconjugated Recombinant Antibody
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人, 小鼠, 大鼠 IHC, StM 宿主: 小鼠 Monoclonal rNX2-1-690 unconjugated Recombinant Antibody
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-312R unconjugated Recombinant Antibody
anti-NK2 Homeobox 1 (NKX2-1) (AA 1-30), (N-Term) antibodyNKX2-1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB28559 unconjugated
anti-NK2 Homeobox 1 (NKX2-1) antibodyNKX2-1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NK2 Homeobox 1 (NKX2-1) (AA 77-158) antibodyNKX2-1 适用: 人 WB, IF, ELISA 宿主: 小鼠 Monoclonal 2B9 unconjugated
anti-NK2 Homeobox 1 (NKX2-1) (N-Term) antibodyNKX2-1 适用: 人 IHC, IHC (p), HIER 宿主: 小鼠 Monoclonal SPT24 unconjugated
anti-NK2 Homeobox 1 (NKX2-1) (AA 2-1) antibodyNKX2-1 适用: 人 WB, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Positive Control: MAD109, MLE-15, H441-4 or H345 cells. Normal thyroid or lung.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
- 别名
- NKX2-1 (NKX2-1 产品)
- 别名
- BCH antibody, BHC antibody, NK-2 antibody, NKX2.1 antibody, NKX2A antibody, TEBP antibody, TITF1 antibody, TTF-1 antibody, TTF1 antibody, titf1-A antibody, Xnkx-2.1 antibody, NKX2-1 antibody, LOC100227803 antibody, AV026640 antibody, Nkx2.1 antibody, T/EBP antibody, Titf1 antibody, Ttf-1 antibody, nk2.1a antibody, nkx2.1 antibody, nkx2.4a antibody, titf1 antibody, titf1a antibody, NK2 homeobox 1 antibody, NK2 homeobox 1 L homeolog antibody, NK2 homeobox 4b antibody, NKX2-1 antibody, nkx2-1.L antibody, Nkx2-1 antibody, nkx2.4b antibody
- 分子量
- 40kDa
- 基因ID
- 7080
- UniProt
- P43699
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
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