STAT2 抗体
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- 抗原 See all STAT2 抗体
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This STAT2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant full-length human STAT2 protein
- 克隆位点
- STAT2-2650
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product STAT2 Primary Antibody
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- 应用备注
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Positive Control: Ramos and Jurkat cell lysates. HeLa cell extract. Human lung carcinoma tissue.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
- 别名
- STAT2 (STAT2 产品)
- 别名
- wu:fj84d07 antibody, p113 antibody, stat2 antibody, 1600010G07Rik antibody, AW496480 antibody, ISGF-3 antibody, P113 antibody, STAT113 antibody, signal transducer and activator of transcription 2 antibody, AGAP000099-PA antibody, stat2 antibody, STAT2 antibody, Stat2 antibody
- 背景
- Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
- 分子量
- 113kDa
- 基因ID
- 6773
- UniProt
- P52630
- 途径
- JAK/STAT Signaling, Hepatitis C, CXCR4-mediated Signaling Events
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