SREBF2 抗体
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- 抗原 See all SREBF2 抗体
- SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SREBF2 antibody is un-conjugated
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应用范围
- ELISA, Coating (Coat)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant full-length human SREBF2 protein
- 克隆位点
- SREBP2-1579
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product SREBF2 Primary Antibody
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- 应用备注
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Positive Control: Ubiqutious expression in adult and fetal tissues. Hep2 or HeLa cells.
Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))
- 别名
- SREBF2 (SREBF2 产品)
- 别名
- SREBF2 antibody, srebp2 antibody, SREBP2 antibody, zgc:158371 antibody, AI608257 antibody, SREBP-2 antibody, SREBP2gc antibody, bHLHd2 antibody, lop13 antibody, nuc antibody, Srebf2_retired antibody, sterol regulatory element binding transcription factor 2 antibody, sterol regulatory element binding factor 2 antibody, sterol regulatory element binding transcription factor 2 L homeolog antibody, SREBF2 antibody, srebf2 antibody, Srebf2 antibody, srebf2.L antibody
- 背景
- The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1). When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors, designated SREBP-1 and SREBP-2. SREBP-1 and SREBP-2 have been shown to have the same specificity for SRE-1 in vitro and to activate the transcription of reporter genes containing SRE-1 in the same way.
- 分子量
- 68/125kDa
- 基因ID
- 6721
- UniProt
- Q12772
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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