Recombinant Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体
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- 抗原 See all Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) 抗体
- Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)
- 抗体类型
- Recombinant Antibody
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抗原表位
- AA 356-475
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant fragment (around aa356-475) of human SPTBN2 protein (exact sequence is proprietary)
- 克隆位点
- SPTBN2-2979R
- 亚型
- IgG
- Top Product
- Discover our top product SPTBN2 Primary Antibody
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- 应用备注
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Positive Control: HeLa cells. Pancreas or Liver.
Known Application: Western Blot (0.5-1.0 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)
- 别名
- SPTBN2 (SPTBN2 产品)
- 别名
- Spnb3 antibody, mKIAA0302 antibody, GTRAP41 antibody, SCA5 antibody, spectrin beta, non-erythrocytic 2 antibody, spectrin, beta, non-erythrocytic 2 antibody, Sptbn2 antibody, SPTBN2 antibody
- 背景
- Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II) four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.
- 分子量
- 246kDa
- 基因ID
- 6712
- UniProt
- O15020
- 途径
- Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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