Recombinant Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体
-
- 抗原 See all Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) 抗体
- Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)
- 抗体类型
- Recombinant Antibody
-
抗原表位
- AA 356-475
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- 非结合性
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Coating (Coat)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant fragment (around aa356-475) of human SPTBN2 protein (exact sequence is proprietary)
- 克隆位点
- RSPTBN2-1778
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product SPTBN2 Primary Antibody
-
-
- 应用备注
-
Positive Control: PANC-1, HeLa, PC-3 cells. Human brain, pancreas or liver tissues (IHC).
Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
-
- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
-
- 抗原
- Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)
- 别名
- SPTBN2 (SPTBN2 产品)
- 别名
- Spnb3 antibody, mKIAA0302 antibody, GTRAP41 antibody, SCA5 antibody, spectrin beta, non-erythrocytic 2 antibody, spectrin, beta, non-erythrocytic 2 antibody, Sptbn2 antibody, SPTBN2 antibody
- 背景
- Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II) four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin and spectrin are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin I (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin III is highly homologous to both spectrin I and spectrin II. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.
- 分子量
- 246kDa
- 基因ID
- 6712
- UniProt
- O15020
- 途径
- Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
-