Spectrin beta Chain, Erythrocyte (SPTB) 抗体
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- 抗原 See all Spectrin beta Chain, Erythrocyte (SPTB) 抗体
- Spectrin beta Chain, Erythrocyte (SPTB)
- 适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Coating (Coat), ELISA, Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Red cell membranes
- 克隆位点
- RG-26
- 亚型
- IgG2a kappa
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anti-Spectrin beta Chain, Erythrocyte (SPTB) antibody
SPTB 适用: 人 WB, IP, IHC 宿主: 小鼠 Monoclonal DB2 unconjugated
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- 应用备注
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Positive Control: Jurkat whole cell lysate (WB). Human colon carcinoma tissue (IHC).
Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL), ,Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- Spectrin beta Chain, Erythrocyte (SPTB)
- 别名
- SPTB (SPTB 产品)
- 别名
- AI842465 antibody, D330027P03Rik antibody, Gm1301 antibody, Spnb-1 antibody, Spnb1 antibody, ja antibody, jaundiced antibody, mKIAA4219 antibody, EL3 antibody, HS2 antibody, HSPTB1 antibody, SPH2 antibody, spectrin beta, erythrocytic antibody, spectrin, beta, erythrocytic antibody, SPTB antibody, Sptb antibody
- 背景
- Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements, forming a scaffolding and playing an important role in maintenance of plasma membrane integrity and cytoskeletal structure. In certain types of brain injury such as diffuse axonal injury, spectrin is irreversibly cleaved by the proteolytic enzyme calpain, destroying the cytosketelon. Spectrin cleavage causes the membrane to form blebs and ultimately to be degraded, usually leading to cell death.
- 分子量
- 246kDa
- 基因ID
- 6710
- UniProt
- O15020
- 途径
- Regulation of Actin Filament Polymerization
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