Fascin 抗体
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- 抗原 See all Fascin (FSCN1) 抗体
- Fascin (FSCN1)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Fascin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Staining Methods (StM)
- 特异性
- Recognizes a protein of 55 kDa, which is identified as fascin-1. Its actin binding ability is regulated by phosphorylation. Antibody to fascin-1 is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin's disease. It is uniformly negative in lymphoid cells, plasma cells, and myeloid cells. Fascin-1 is also expressed in dendritic cells. This marker may be helpful to distinguish between Hodgkin lymphoma and non-Hodgkin lymphoma in difficult cases. Also, the lack of expression of fascin-1 in the neoplastic follicles in follicular lymphoma may be helpful in distinguishing these lymphomas from reactive follicular hyperplasia in which the number of follicular dendritic cells is normal or increased. Antibody to fascin-1 has been suggested as a prognostic marker in neuroendocrine neoplasms of the lung as well as in ovarian cancer. Fascin-1 expression may be induced by Epstein-Barr virus (EBV) infection of B cells with the possibility that viral induction of fascin in lymphoid or other cell types must also be considered in EBV-positive cases.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Full length recombinant human FSCN1 protein
- 克隆位点
- FSCN1-417
- 亚型
- IgG2a kappa
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anti-Fascin (FSCN1) antibody
FSCN1 适用: 人, 大鼠 WB, IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal FSCN1-418 unconjugated
anti-Fascin (FSCN1) (AA 11-110) antibodyFSCN1 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) antibodyFSCN1 适用: 人 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal FSCN1-416 unconjugated
anti-Fascin (FSCN1) (AA 394-493) antibodyFSCN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) (pSer39) antibodyFSCN1 适用: 人, 小鼠 WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) (AA 322-350) antibodyFSCN1 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) (AA 2-187) antibodyFSCN1 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) (AA 93-142) antibodyFSCN1 适用: 人, 小鼠, 大鼠, 豚鼠, 犬, 马, 斑马鱼, 猴, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Fascin (FSCN1) antibodyFSCN1 适用: 人, 大鼠 IHC, IHC (p) 宿主: 小鼠 Monoclonal FCN01 unconjugated
anti-Fascin (FSCN1) (AA 277-396) antibodyFSCN1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Positive Control: HeLa, MCF-7, PC-3 or BEWO cells. Hodgkin's lymphoma, Ovarian or Testicular Carcinoma.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1.0 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- Fascin (FSCN1)
- 别名
- FSCN1 (FSCN1 产品)
- 别名
- CG15331 antibody, CG1536 antibody, CG32858 antibody, Dmel\\CG32858 antibody, SN antibody, Sn antibody, fs(1)A1057 antibody, fs(1)K1421 antibody, fs(1)K418 antibody, fs(1)K473 antibody, fs(1)K743 antibody, fs(1)M45 antibody, p55 antibody, snl antibody, MGC75811 antibody, fscn1 antibody, sb:cb589 antibody, zgc:153632 antibody, AI663989 antibody, Fan1 antibody, fascin-1 antibody, Fascin antibody, fscn antibody, FAN1 antibody, HSN antibody, SNL antibody, fascin antibody, singed antibody, fascin actin-bundling protein 1 antibody, fascin actin-bundling protein 1a antibody, fascin actin-bundling protein 1 L homeolog antibody, sn antibody, fscn1 antibody, fscn1a antibody, Fscn1 antibody, fscn1.L antibody, FSCN1 antibody
- 分子量
- 55kDa
- 基因ID
- 6624
- UniProt
- Q16658
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