s100a4 抗体
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- 抗原 See all s100a4 (S100A4) 抗体
- s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This s100a4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant human S100A4 full length protein
- 克隆位点
- CPTC-S100A4-3
- 亚型
- IgG2c kappa
- Top Product
- Discover our top product S100A4 Primary Antibody
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- 应用备注
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Positive Control: T98G, HeLa, A549 or A375 cells. Placenta, small intestine.
Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
- 别名
- S100A4 (S100A4 产品)
- 别名
- 18A2 antibody, 42A antibody, CAPL antibody, FSP1 antibody, MTS1 antibody, P9KA antibody, PEL98 antibody, 42a antibody, Capl antibody, FSp1 antibody, Mts1 antibody, PeL98 antibody, metastasin antibody, pk9a antibody, S100A4 antibody, P9ka antibody, RNP9KA antibody, S100 calcium binding protein A4 antibody, S100 calcium-binding protein A4 antibody, S100A4 antibody, S100a4 antibody
- 背景
- S100A4 belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100A4 has been implicated in the progression and prognosis of several forms of human cancer, e.g. breast, colorectal, gastric, pancreatic and bladder cancer, SCLC and oesophageal squamous cell carcinoma, among others. Poor prognosis associated with high S100A4 expression is accompanied by clear signs of disease progression, e.g. high histological and clinical grades and involvement of lymph nodes.Also indicative of poor prognosis is high S100A4 expression coupled with reduced E-cadherin expression in pancreatic, oral squamous cell carcinoma and in melanoma. S100A4 expression is inversely related with expression of metastasis suppressor nm23 and with prognosis of breast cancer. S100A4 is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression.
- 分子量
- 12kDa
- 基因ID
- 6275
- UniProt
- P26447
- 途径
- S100 Proteins
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