beta-2 Microglobulin 抗体
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- 抗原 See all beta-2 Microglobulin (B2M) 抗体
- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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适用
- 人, Non-Human Primate
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This beta-2 Microglobulin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)
- 特异性
- Recognizes a protein of 12 kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 Molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 Molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 Molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Full length recombinant human B2M protein
- 克隆位点
- B2M-961
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product B2M Primary Antibody
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anti-beta-2-Microglobulin (B2M) (AA 1-119) antibody
B2M 适用: 人 WB, ELISA, IF, IHC (p), RNAi, PLA 宿主: 小鼠 Monoclonal 3F9-2C2 unconjugated
anti-beta-2-Microglobulin (B2M) (AA 21-100) antibodyB2M 适用: 人 WB, FACS, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 4G5A1 unconjugated
anti-beta-2-Microglobulin (B2M) (AA 21-100) antibodyB2M 适用: 人 WB, FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 3G5H8 unconjugated
anti-beta-2-Microglobulin (B2M) (AA 22-119) antibodyB2M 适用: 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A2 unconjugated
anti-beta-2-Microglobulin (B2M) (AA 22-119) antibodyB2M 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-beta-2-Microglobulin (B2M) antibodyB2M 适用: 人, Non-Human Primate FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal rB2M-961 unconjugated Recombinant Antibody
anti-beta-2-Microglobulin (B2M) antibodyB2M 适用: 人, Non-Human Primate IHC, StM 宿主: 小鼠 Monoclonal B2M-1118 unconjugated
anti-beta-2-Microglobulin (B2M) antibodyB2M 适用: 人 WB, FACS, ELISA, IP, IHC (p), ICC, RIA 宿主: 小鼠 Monoclonal B2M-01 unconjugated
anti-beta-2-Microglobulin (B2M) antibody (Biotin)B2M 适用: 人 WB, FACS, ELISA, IP, IHC (p), ICC 宿主: 小鼠 Monoclonal B2M-01 Biotin
anti-beta-2-Microglobulin (B2M) antibodyB2M 适用: 人, Non-Human Primate FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal B2M-961 unconjugated
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- 应用备注
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Positive Control: HL-60 or HeLa cells. Melanomas and Lymphoma. Carcinoma of Stomach, Cervix, Endometrial, Kidney or Colon.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-4 μg/mL), ,Western Blot (0.5-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
- 别名
- B2M (B2M 产品)
- 别名
- Ly-m11 antibody, beta2-m antibody, beta2m antibody, bwm antibody, wu:fa94c05 antibody, wu:fb10a09 antibody, b2m-W01 antibody, b2m-W03 antibody, b2m-Z01 antibody, b2m-Z02 antibody, b2m-Z03 antibody, B2M antibody, b2m antibody, B2MG antibody, wu:fb66f11 antibody, wu:fj01f08 antibody, zgc:64161 antibody, b-2-m antibody, beta-2-microglobulin antibody, beta-2 microglobulin antibody, beta-2-microglobulin S homeolog antibody, beta-2-microglobulin, like antibody, B2M antibody, B2m antibody, b2m antibody, b2m.S antibody, b2ml antibody
- 分子量
- 12kDa
- 基因ID
- 567
- UniProt
- P61769
- 途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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