UACA 抗体
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- 抗原 See all UACA 抗体
- UACA
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This UACA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Nuclei of myeloid leukemia biopsy cells
- 克隆位点
- AE-5
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product UACA Primary Antibody
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- 应用备注
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Positive Control: HeLa or 293T cells. Highly expressed in skeletal muscle, heart, kidney and pancreas. Also expressed in epidermal melanocytes, eye muscles and thyroid follicular cells.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1.0 μg/mL), Western Blot (0.5-1 μg/mL),Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- UACA
- 别名
- UACA (UACA 产品)
- 别名
- NUCLING antibody, 2700059D02Rik antibody, nucling antibody, RGD1560011 antibody, uveal autoantigen with coiled-coil domains and ankyrin repeats antibody, UACA antibody, Uaca antibody
- 背景
- UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
- 分子量
- 160kDa
- 基因ID
- 55075
- 途径
- Positive Regulation of Endopeptidase Activity
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