Recombinant ATRX 抗体
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- 抗原 See all ATRX 抗体
- ATRX (helicase 2, X-linked (ATRX))
- 抗体类型
- Recombinant Antibody
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This ATRX antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunostaining (ISt), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant human ATRX protein
- 克隆位点
- ATRX-2900R
- 亚型
- IgG
- Top Product
- Discover our top product ATRX Primary Antibody
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- 应用备注
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Positive Control: Raji, HeLa or A431 cells. Pancreas, Adrenal, Ovary, Kidney, Prostate or Stomach.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA Buffer, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- ATRX (helicase 2, X-linked (ATRX))
- 别名
- ATRX (ATRX 产品)
- 别名
- ATR2 antibody, JMS antibody, MRXHF1 antibody, RAD54 antibody, RAD54L antibody, SFM1 antibody, SHS antibody, XH2 antibody, XNP antibody, ZNF-HX antibody, 4833408C14Rik antibody, AI447451 antibody, DXHXS6677E antibody, HP1-BP38 antibody, Hp1bp2 antibody, Hp1bp38 antibody, MRXS3 antibody, Rad54 antibody, Xnp antibody, atrx antibody, rad54 antibody, atrxl antibody, wu:fb26e12 antibody, wu:fb52h08 antibody, wu:fb72g09 antibody, wu:fb94e07 antibody, zgc:66223 antibody, ATRX, chromatin remodeler antibody, alpha thalassemia/mental retardation syndrome X-linked L homeolog antibody, alpha thalassemia/mental retardation syndrome X-linked homolog (human) antibody, ATRX antibody, Atrx antibody, atrx.L antibody, atrx antibody
- 背景
- ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, ATRX contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, ATRX predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 thalassemia or ATRX syndrome
- 分子量
- 280kDa
- 基因ID
- 546
- UniProt
- P46100
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