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Progesterone Receptor 抗体 (AA 483-571)

PGR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PGR-2694 unconjugated
产品编号 ABIN6940299
发货至: 中国
  • 抗原 See all Progesterone Receptor (PGR) 抗体
    Progesterone Receptor (PGR)
    抗原表位
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    AA 483-571
    适用
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    宿主
    • 188
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    小鼠
    克隆类型
    • 185
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    单克隆
    标记
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    This Progesterone Receptor antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC), Staining Methods (StM)
    特异性
    This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than estrogen receptor (ER) alone. This MAb is excellent for immunohistochemical staining of formalin-fixed tissues.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant fragment of human Progesterone Receptor (PGR) protein (around aa 483-571) (exact sequence is proprietary)
    克隆位点
    PGR-2694
    亚型
    IgG1 kappa
    Top Product
    Discover our top product PGR Primary Antibody
  • 应用备注

    Positive Control: T47-D cells. Endometrial or Breast Carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT) (our BEST clone)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    Progesterone Receptor (PGR)
    别名
    PGR (PGR 产品)
    别名
    NR3C3 antibody, PR antibody, 9930019P03Rik antibody, BB114106 antibody, ENSMUSG00000074510 antibody, PR-A antibody, PR-B antibody, XPR-1 antibody, pgr antibody, xpr-2 antibody, LOC443444 antibody, PGR antibody, pg antibody, pr antibody, gb:dq017620 antibody, progesterone receptor antibody, progesterone receptor L homeolog antibody, PGR antibody, Pgr antibody, pgr.L antibody, pgr antibody
    分子量
    PR-A (81kDa) and PR-B (116kDa).
    基因ID
    5241
    UniProt
    P06401
    途径
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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