Progesterone Receptor 抗体 (AA 483-571)
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- 抗原 See all Progesterone Receptor (PGR) 抗体
- Progesterone Receptor (PGR)
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抗原表位
- AA 483-571
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Progesterone Receptor antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 特异性
- This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than estrogen receptor (ER) alone. This MAb is excellent for immunohistochemical staining of formalin-fixed tissues.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant fragment of human Progesterone Receptor (PGR) protein (around aa 483-571) (exact sequence is proprietary)
- 克隆位点
- PGR-2694
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product PGR Primary Antibody
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- 应用备注
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Positive Control: T47-D cells. Endometrial or Breast Carcinoma.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT) (our BEST clone)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- Progesterone Receptor (PGR)
- 别名
- PGR (PGR 产品)
- 别名
- NR3C3 antibody, PR antibody, 9930019P03Rik antibody, BB114106 antibody, ENSMUSG00000074510 antibody, PR-A antibody, PR-B antibody, XPR-1 antibody, pgr antibody, xpr-2 antibody, LOC443444 antibody, PGR antibody, pg antibody, pr antibody, gb:dq017620 antibody, progesterone receptor antibody, progesterone receptor L homeolog antibody, PGR antibody, Pgr antibody, pgr.L antibody, pgr antibody
- 分子量
- PR-A (81kDa) and PR-B (116kDa).
- 基因ID
- 5241
- UniProt
- P06401
- 途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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