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NADPH Oxidase 4 抗体

NOX4 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal NOX4-1245 unconjugated
产品编号 ABIN6940247
发货至: 中国
  • 抗原 See all NADPH Oxidase 4 (NOX4) 抗体
    NADPH Oxidase 4 (NOX4)
    适用
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    宿主
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    小鼠
    克隆类型
    • 80
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    单克隆
    标记
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    This NADPH Oxidase 4 antibody is un-conjugated
    应用范围
    • 80
    • 41
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    Western Blotting (WB), ELISA, Coating (Coat)
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant human NOX4 protein
    克隆位点
    NOX4-1245
    亚型
    IgG2b kappa
    Top Product
    Discover our top product NOX4 Primary Antibody
  • 应用备注

    Positive Control: PC-12, JAR cells. Kidney.

    Known Application: ELISA (For coating, order Ab without BSA)Western Blot (0.5-1 μg/mL)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    NADPH Oxidase 4 (NOX4)
    别名
    NOX4 (NOX4 产品)
    别名
    KOX antibody, KOX-1 antibody, RENOX antibody, AI648021 antibody, nox4 antibody, NOX4 antibody, NADPH oxidase 4 antibody, NOX4 antibody, Nox4 antibody, nox4 antibody, PTRG_09562 antibody
    背景
    The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.
    分子量
    70kDa
    基因ID
    50507
    UniProt
    Q9NPH5
    途径
    Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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