CD207 抗体 (AA 74-213)
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- 抗原 See all CD207 抗体
- CD207 (CD207 Molecule, Langerin (CD207))
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抗原表位
- AA 74-213
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD207 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Coating (Coat)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
- 克隆位点
- LGRN-1821
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product CD207 Primary Antibody
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- 应用备注
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Positive Control: HeLa or A549 cells (WB).
Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- CD207 (CD207 Molecule, Langerin (CD207))
- 别名
- CD207 (CD207 产品)
- 别名
- CD207 antibody, CLEC4K antibody, RGD1565913 antibody, CD207 molecule antibody, CD207 antigen antibody, CD207 antibody, Cd207 antibody
- 背景
- Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.
- 分子量
- 48kDa
- 基因ID
- 50489
- UniProt
- Q9UJ71
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