电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

NKX3-1 抗体 (AA 92-224)

NKX3-1 适用: 人 ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal NKX3-1-3350 unconjugated
产品编号 ABIN6940208
发货至: 中国
  • 抗原 See all NKX3-1 抗体
    NKX3-1 (NK3 Homeobox 1 (NKX3-1))
    抗原表位
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 92-224
    适用
    • 70
    • 19
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 57
    • 22
    • 1
    小鼠
    克隆类型
    • 56
    • 24
    单克隆
    标记
    • 46
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NKX3-1 antibody is un-conjugated
    应用范围
    • 57
    • 44
    • 14
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Coating (Coat), Staining Methods (StM)
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant fragment (around aa 92-224) of human NKX3.1 protein (exact sequence is proprietary)
    克隆位点
    NKX3-1-3350
    亚型
    IgG2b kappa
    Top Product
    Discover our top product NKX3-1 Primary Antibody
  • 应用备注

    Positive Control: Highly expressed in the prostate and at a lower level in the testis.

    Known Application: ELISA (For coating, order Ab without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    NKX3-1 (NK3 Homeobox 1 (NKX3-1))
    别名
    NKX3-1 (NKX3-1 产品)
    别名
    Xbagpipe antibody, Xbap antibody, bagpipe antibody, koza antibody, nkx3-1 antibody, nkx3.1 antibody, si:ch211-67o1.2 antibody, nkx3a antibody, MGC53041 antibody, MGC97890 antibody, Bax antibody, NKX3.1 antibody, NKX3A antibody, Nkx-3.1 antibody, BAPX2 antibody, NKX3 antibody, NK3 homeobox 1 L homeolog antibody, NK3 homeobox 1 antibody, NK-3 transcription factor, locus 1 (Drosophila) antibody, nkx3-1.L antibody, NKX3-1 antibody, nkx3-1 antibody, Nkx3-1 antibody
    背景
    NKX3.1 is a prostate specific gene encoding a transcription factor that plays an important role in normal prostate development and carcinogenesis. It is a prostatic tumor suppressor gene located on chromosome 8p21.2, which frequently undergoes a loss of heterozygosity. NKX3.1 expression is highly restricted in prostate epithelial cells and therefore can be used as a diagnostic biomarker for prostate cancer and other metastatic lesions of prostatic origin. Furthermore, NKX3.1 shows better sensitivity than Prostate Specific Antigen (PSA) for identifying metastatic prostatic adenocarcinoma. This suggests that immunohistochemical staining of NKX3.1, along with other prostate-restricted markers, may be valuable for the definitive determination of prostatic origin in poorly differentiated metastatic carcinomas.
    分子量
    35kDa
    基因ID
    4824
    UniProt
    Q99801
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
You are here:
客服