Nkx2-2 抗体 (AA 1-119)
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- 抗原 See all Nkx2-2 抗体
- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
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抗原表位
- AA 1-119
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This Nkx2-2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 特异性
- Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant human NKX2.2 protein fragment (around aa1-119) (exact sequence is proprietary)
- 克隆位点
- NX2-2198R
- 亚型
- IgG
- Top Product
- Discover our top product Nkx2-2 Primary Antibody
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- 应用备注
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Positive Control: Pancreas or Ewing's sarcoma.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
- 别名
- NKX2-2 (Nkx2-2 产品)
- 别名
- XeNK-2 antibody, Xnkx2.2 antibody, nkx2-2-A antibody, nkx2.2 antibody, NKX-2.2 antibody, NKX2.2 antibody, NKX2B antibody, Nkx-2.2 antibody, Nkx2.2 antibody, tinman antibody, id:ibd5090 antibody, nk2.2 antibody, nkx2-2 antibody, wu:fc83b01 antibody, zgc:136536 antibody, NK2 homeobox 2 S homeolog antibody, NK2 homeobox 2 antibody, NK2 homeobox 2a antibody, nkx2-2.S antibody, NKX2-2 antibody, Nkx2-2 antibody, nkx2.2a antibody
- 分子量
- 40-50kDa
- 基因ID
- 4821
- UniProt
- O95096
- 途径
- Dopaminergic Neurogenesis
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